Systematic proteome quantification for human & mouse

Large-scale absolute quantification for human and mouse samples.

SysQuan quantifies your samples against a pre-quantified, K6-labeled mouse reference proteome, with heavy ¹³C₆-lysine internal standards for thousands of proteins across multiple tissues. No synthetic peptides, ~100× lower cost. Search the atlas to confirm coverage, then request a quote.

Is your protein in the database?
Examples:
Choose your organism

Two atlases, one method.

Pick the species you're working in to browse its coverage and open the searchable database.

SysQuan Human
Live

Light (unlabeled) human tissue mixed with the pre-quantified, K6-labeled mouse reference proteome for proteome-wide absolute quantification.

10,231
Quantifiable
2,905
Assays
7
Tissues
Kidney 8,844 Lung 8,798 Spleen 7,935 Liver 7,122 Heart 7,057 DBS 2,127 Plasma 1,225
Browse the human database →
SysQuan Mouse
Live

Light mouse tissue against the same K6-labeled mouse reference proteome. Currently brain regions plus liver, lung and kidney, expanding.

14,474
Quantifiable
2,794
Assays
6
Tissues
Cerebrum 10,280 Brain stem 10,062 Cerebellum 9,629 Lung 8,730 Liver 8,636 Kidney 7,679
Browse the mouse database →
Get started

Quantify your proteins with SysQuan.

Send us your sample, or buy the kit and run it yourself, then process your data against the atlas. Absolute quantification, no synthetic peptides, ~100× lower cost.

Email us Request a quote
The workflow

From your sample to absolute concentrations.

No synthetic peptides and no per-target standard curves. The pre-quantified K6 reference proteome supplies the heavy internal standard for every peptide.

1

Submit a sample, or buy the kit

Send us light (unlabeled) tissue, plasma, or dried blood spots, or run the kit yourself and send the data. Check coverage in the atlas first.

2

Mix with the K6 reference proteome

Your sample is combined with a pre-quantified, K6-labeled (¹³C₆-lysine) mouse tissue proteome. Every peptide gains a heavy internal standard at a known concentration.

3

Quantify by MRM, PRM-PASEF or DIA

Optimized targeted assays (MRM, PRM-PASEF) and large-scale DIA yield light/heavy ratios, converted to absolute concentrations for your proteins of interest.